Botox® For Cosmetics

Botox® is now the most widely used cosmetic procedure in the world. The cosmetic use of Botox® started in 1987 when the husband and wife team of Canadian doctors, Drs. Carruthers (Vancouver Ophthalmologist and Dermatologist) noted by accident that patients treated for Blepharospasm had also had a vast improvement of dynamic wrinkles of the glabella.


Botox® is the brand name of the commercial form of Botulinum toxin (BTX), which is a neurotoxic protein produced by the bacterium Clostridium botulinum. Botox® works to inhibit the release of a chemical between neurons thus interfering with nerve conduction of a signal resulting in paralysis. Although this may sound concerning, the safety margin of Botox® is about 100:1. It would take about 100 times the therapeutic dose to poison someone with Botox. The safety margin with others common medicines is around 20:1 (Aspirin and Tylenol).